We explored the effects of human placenta hydrolysate (hPH) on stress-induced depressive behaviors in rats. Through a well-structured methodology that included controlled stress sessions and behavioral tests, we observed that hPH significantly reduced immobility time in the forced swimming test, indicating potential anti-stress benefits.
Additionally, we noted hPH slightly decreased anxiety behaviors and improved antioxidant levels in the brain. This study suggests that hPH could play a role in addressing stress-related conditions like chronic fatigue syndrome. However, further research is needed to fully understand its mechanisms.
Read More
7
Qiye Shen'an Pian shows promise in CFS
Effects of Qiye Shen'an Pian Combined with Glutamate and Vitamin B1 on Fatigue State, Immune Function and Quality of Life in Patients with Chronic Fatigue Syndrome.
This study evaluated how Qiye Shen'an Pian, paired with glutathione and vitamin B1, affects patients with chronic fatigue syndrome (CFS). We conducted a trial with 106 CFS patients, dividing them into two groups for an 8-week treatment.
The findings showed that patients receiving the combination therapy experienced marked improvements in immune function and reduced fatigue. Key indicators like immune cell levels and antioxidant activity saw significant enhancements, suggesting this approach could effectively alleviate CFS symptoms.
Ultimately, the combination therapy offers promising insights for better managing chronic fatigue syndrome.
Read More
8
HemoHIM shows potential antifatigue effects
Antioxidant and antifatigue effect of a standardized fraction (HemoHIM) from , , and .
We investigated the antifatigue effects of HemoHIM, a herbal preparation, on chronic fatigue syndrome models. Through a study involving various dosages on mice, we observed that HemoHIM significantly improved endurance and restored antioxidant enzyme levels in muscle cells.
In the tests, mice receiving HemoHIM showed noteworthy performance improvements, especially at higher dosages. However, while promising, the overall impact on chronic fatigue syndrome symptoms and longer-term benefits still need further exploration.
Read More
Most Useful Reviews
10
Restored physical strength
7 people found this helpful
I believed my lack of stamina resulted from insufficient exercise, only to discover I was deficient in this vital ingredient. Initially slow at climbing stairs, I can now run and ascend stairs effortlessly—much like I did two decades ago. I'm astonished at how quickly I've recovered from fatigue and illness!
Read More
9
Fatigue from corona improved.
4 people found this helpful
I began using this to alleviate fatigue stemming from post-corona effects. After two weeks, I found all symptoms resolved! I wish to continue using it as a preventive measure going forward.
Read More
9
Fatigue noticeably reduced.
3 people found this helpful
I've noticed my fatigue has significantly decreased! I plan on continuing with just one pill a day. It can be taken on an empty stomach without issue.
We investigated the antifatigue effects of HemoHIM, a herbal preparation, on chronic fatigue syndrome models. Through a study involving various dosages on mice, we observed that HemoHIM significantly improved endurance and restored antioxidant enzyme levels in muscle cells.
In the tests, mice receiving HemoHIM showed noteworthy performance improvements, especially at higher dosages. However, while promising, the overall impact on chronic fatigue syndrome symptoms and longer-term benefits still need further exploration.
Read More
7
Qiye Shen'an Pian shows promise in CFS
Effects of Qiye Shen'an Pian Combined with Glutamate and Vitamin B1 on Fatigue State, Immune Function and Quality of Life in Patients with Chronic Fatigue Syndrome.
This study evaluated how Qiye Shen'an Pian, paired with glutathione and vitamin B1, affects patients with chronic fatigue syndrome (CFS). We conducted a trial with 106 CFS patients, dividing them into two groups for an 8-week treatment.
The findings showed that patients receiving the combination therapy experienced marked improvements in immune function and reduced fatigue. Key indicators like immune cell levels and antioxidant activity saw significant enhancements, suggesting this approach could effectively alleviate CFS symptoms.
Ultimately, the combination therapy offers promising insights for better managing chronic fatigue syndrome.
Read More
7
hPH may combat stress effects
Anti-stress effects of human placenta extract: possible involvement of the oxidative stress system in rats.
We explored the effects of human placenta hydrolysate (hPH) on stress-induced depressive behaviors in rats. Through a well-structured methodology that included controlled stress sessions and behavioral tests, we observed that hPH significantly reduced immobility time in the forced swimming test, indicating potential anti-stress benefits.
Additionally, we noted hPH slightly decreased anxiety behaviors and improved antioxidant levels in the brain. This study suggests that hPH could play a role in addressing stress-related conditions like chronic fatigue syndrome. However, further research is needed to fully understand its mechanisms.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 47 Reviews
7.5
All Reviews
Positive Reviews
Negative Reviews
10
Restored physical strength
7 people found this helpful
I believed my lack of stamina resulted from insufficient exercise, only to discover I was deficient in this vital ingredient. Initially slow at climbing stairs, I can now run and ascend stairs effortlessly—much like I did two decades ago. I'm astonished at how quickly I've recovered from fatigue and illness!
Read More
9
Fatigue from corona improved.
4 people found this helpful
I began using this to alleviate fatigue stemming from post-corona effects. After two weeks, I found all symptoms resolved! I wish to continue using it as a preventive measure going forward.
Read More
9
Fatigue noticeably reduced.
3 people found this helpful
I've noticed my fatigue has significantly decreased! I plan on continuing with just one pill a day. It can be taken on an empty stomach without issue.
Read More
9
Extraordinary fatigue recovery.
2 people found this helpful
After pairing this with CGN silymarin, I experienced remarkable recovery from fatigue and found it easier to rise in the morning. Although the tablets are a bit large, the effectiveness outweighs the size concern since only one daily tablet is required.
Read More
9
Skin improved and fatigue decreased.
2 people found this helpful
Following my dermatologist's recommendation, I began taking this. I have received numerous compliments regarding my skin's improvement and it's also significantly reduced my fatigue, making my mornings much easier.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
L-glutathione is a powerful antioxidant that plays a crucial role in cellular health by protecting cells from oxidative stress and damage caused by free radicals. It is a tripeptide composed of three amino acids: cysteine, glutamine, and glycine. Naturally produced in the body, L-glutathione is found in higher concentrations in the liver, where it aids in detoxification processes, immune system function, and the metabolism of various compounds. As we age or face various environmental stresses, our body's levels of glutathione may decrease, leading to potential health implications.
Based on user reviews, the timeline for experiencing results from this supplement varies, but many report noticeable effects within as little as one to two weeks of consistent use. For instance, one user mentioned that after two weeks of taking the supplement, all symptoms of fatigue stemming from post-corona effects had resolved (Read Review). Another review highlights significant improvement just after seven days, with the user experiencing a remarkable boost in energy levels (Read Review).
Moreover, several users have commented on feeling a reduction in fatigue and increased energy relatively quickly, within days or weeks of starting the regimen (Read Review; Read Review). While individual experiences can differ, many say they began to notice changes in their stamina and overall fatigue levels shortly after incorporating the supplement into their routine.
This supplement is gaining attention in the scientific community for its potential benefits in managing Chronic Fatigue Syndrome (CFS). A study involving 106 CFS patients demonstrated that a combination of Qiye Shen'an Pian, glutathione, and vitamin B1 led to significant improvements in immune function and reduced fatigue levels after an 8-week treatment period. The enhancements in immune cell levels and antioxidant activity suggest that this combined approach could be a viable strategy for alleviating CFS symptoms ([1]).
Additionally, another herbal preparation known as HemoHIM has shown promising effects in CFS models through an experiment on mice. The results indicated improved endurance and antioxidant levels, but further research is necessary to explore the long-term benefits in humans ([2]). While preliminary findings are encouraging, the need for more extensive studies remains, particularly for understanding the efficacy and mechanisms of such supplements in treating CFS.
Users have reported a variety of improvements in their symptoms after taking the supplement, particularly regarding fatigue and energy levels. For instance, one user shared an inspiring transformation, revealing that after experiencing chronic fatigue, they were able to resume running and climbing stairs effortlessly, akin to their younger self (Read Review). Similarly, multiple people noted a significant reduction in fatigue and an increase in their overall energy, with one individual mentioning they no longer dreaded their morning routines thanks to improved stamina (Read Review; Read Review).
Additionally, many users reported feeling energized after taking the supplement, especially in relation to their daily activities or recovery from exercise and illness. A user specifically stated they felt a "notable increase in energy and reduction in fatigue" after their illness recovery process (Read Review). Despite these positive experiences, it is important to note that individual results can vary widely, as some users did not experience any effects at all, emphasizing that while many find relief and improvement in energy, others may not see the same benefits (Read Review; Read Review).
Users have reported various experiences when combining this supplement with other products to manage Chronic Fatigue Syndrome. Notably, one user found that pairing the supplement with CGN silymarin led to remarkable improvements in fatigue recovery and easier morning wake-ups (Read Review). Another user mentioned taking 500mg of glutathione alongside other supplements for optimal fatigue reduction, noting that the absence of glutathione resulted in the return of chronic fatigue symptoms (Read Review). Additionally, a user reported positive results when combining the supplement with lactic acid bacteria, which significantly aided in recovery after strength training (Read Review).
The consensus seems to indicate that combining this supplement with other complementary supplements can enhance its effectiveness, especially in alleviating fatigue. Users who included glutathione in their regimen specifically noted significant improvements in energy levels and reduction in fatigue symptoms, further corroborating its beneficial role when taken alongside other supportive supplements like alpha-lipoic acid and coenzyme Q10 (Read Review; Read Review). However, it's vital to remember that individual experiences may vary widely, and not all combinations yield the same results.
Based on user reviews, the right dose for L Glutathione to treat Chronic Fatigue Syndrome appears to vary among individuals, but many find success with a daily intake of 500mg. Reviewers note that this dosage effectively alleviates fatigue symptoms, with one user reporting significant improvements in energy levels and overall stamina after incorporating a 500mg dose into their regimen (Read Review). Another review echoes this by highlighting that consuming this amount has been key in combating post-exercise lethargy and maintaining vitality for daily activities (Read Review).
Several users emphasized that just one tablet per day suffices for noticeable results, often stating that they felt revitalized and able to tackle tasks that had previously been challenging due to fatigue (Read Review; Read Review). However, experiences do vary, with some users finding no benefit at all even at doses they adjusted, indicating that individual responses to L Glutathione can significantly differ (Read Review; Read Review). Overall, a daily dose of around 500mg seems advisable based on numerous positive accounts.
9
Fatigue from corona improved.
4 people found this helpful
I began using this to alleviate fatigue stemming from post-corona effects. After two weeks, I found all symptoms resolved! I wish to continue using it as a preventive measure going forward.
9
Energy boost experienced
I purchased this based on reviews, curious to test its efficacy. After just seven days, I experienced a remarkable effect. At 62, I thought I might never enjoy running again as I did ten years ago. Now, I am reordering; glutathione has given me a significant boost of energy, eliminating fatigue and arthritis symptoms. I am baffled by its limited attention. I wholeheartedly recommend it!
9
Fatigue noticeably reduced.
3 people found this helpful
I've noticed my fatigue has significantly decreased! I plan on continuing with just one pill a day. It can be taken on an empty stomach without issue.
9
Improves energy levels
1 people found this helpful
Since taking this regularly, I've noticed my skin appears brighter, and I feel much more energetic. It enhances my immunity, especially under stress or pollution, effectively combating chronic fatigue. I plan to continue using it and recommend it to friends.
10
Restored physical strength
7 people found this helpful
I believed my lack of stamina resulted from insufficient exercise, only to discover I was deficient in this vital ingredient. Initially slow at climbing stairs, I can now run and ascend stairs effortlessly—much like I did two decades ago. I'm astonished at how quickly I've recovered from fatigue and illness!
9
Skin improved and fatigue decreased.
2 people found this helpful
Following my dermatologist's recommendation, I began taking this. I have received numerous compliments regarding my skin's improvement and it's also significantly reduced my fatigue, making my mornings much easier.
9
Extraordinary fatigue recovery.
2 people found this helpful
After pairing this with CGN silymarin, I experienced remarkable recovery from fatigue and found it easier to rise in the morning. Although the tablets are a bit large, the effectiveness outweighs the size concern since only one daily tablet is required.
7.5
Energy returned after illness.
2 people found this helpful
I took this to support my recovery after an illness and felt a notable increase in energy and reduction in fatigue without any side effects. I recommend this company's Glutathione.
0
No results
1 people found this helpful
I must reiterate; I haven't noticed any effects! I can't feel any improvement regarding fatigue recovery or skin clarity! I take one pill daily and have adjusted the dosage, but regardless of my efforts, there have been no changes in my body or skin, which leaves me uncertain about continuing.
0
Little impact
I found it ineffective for recovering from fatigue, and I became even more tired. It also did not help with skin whitening.
10
Top-rated antioxidant
1 people found this helpful
For optimal fatigue reduction, I take 500mg of glutathione alongside other supplements. After running out temporarily, I immediately noticed the return of chronic fatigue symptoms. Glutathione's efficacy is remarkable and well-documented.
7.5
Quick fatigue recovery
1 people found this helpful
I purchased this to aid in recovery from fatigue and improve my skin. While I haven't noticed the skin brightening yet, combining it with lactic acid bacteria in the evening noticeably speeds up my recovery from chronic fatigue after strength training.
9
Efficacy of glutathione highlighted.
3 people found this helpful
I take alpha-lipoic acid and coenzyme Q10, but I find that consuming 500mg of glutathione is key to alleviating fatigue the following day. When I ran out of glutathione, I felt the effects immediately, and its efficacy is clearly the best.
6
Physical fatigue alleviated.
3 people found this helpful
I bought glutathione with NAC! Alongside vitamin C and biotin, I experienced a significant improvement in skin tone. Although I haven't noticed major changes after adjusting my intake, I feel it's remarkably effective against physical fatigue.
10
Effective fatigue relief
It was effective against fatigue. As I age, I often feel fatigued and lack energy, so I started taking this supplement. With just one tablet a day, I noticed improvements in my skin's brightness and my fatigue levels. I attribute the good liver values in my health check-up to glutathione, despite taking various supplements.
0
No results
1 people found this helpful
There’s no effect on fatigue or skin whitening; L-cysteine seems to be more beneficial.
7
Qiye Shen'an Pian shows promise in CFS
Effects of Qiye Shen'an Pian Combined with Glutamate and Vitamin B1 on Fatigue State, Immune Function and Quality of Life in Patients with Chronic Fatigue Syndrome.
This study evaluated how Qiye Shen'an Pian, paired with glutathione and vitamin B1, affects patients with chronic fatigue syndrome (CFS). We conducted a trial with 106 CFS patients, dividing them into two groups for an 8-week treatment.
The findings showed that patients receiving the combination therapy experienced marked improvements in immune function and reduced fatigue. Key indicators like immune cell levels and antioxidant activity saw significant enhancements, suggesting this approach could effectively alleviate CFS symptoms.
Ultimately, the combination therapy offers promising insights for better managing chronic fatigue syndrome.
8
HemoHIM shows potential antifatigue effects
Antioxidant and antifatigue effect of a standardized fraction (HemoHIM) from , , and .
We investigated the antifatigue effects of HemoHIM, a herbal preparation, on chronic fatigue syndrome models. Through a study involving various dosages on mice, we observed that HemoHIM significantly improved endurance and restored antioxidant enzyme levels in muscle cells.
In the tests, mice receiving HemoHIM showed noteworthy performance improvements, especially at higher dosages. However, while promising, the overall impact on chronic fatigue syndrome symptoms and longer-term benefits still need further exploration.
References
Liu J, Liao J, Lin F, Nie C. Effects of Qiye Shen'an Pian Combined with Glutamate and Vitamin B1 on Fatigue State, Immune Function and Quality of Life in Patients with Chronic Fatigue Syndrome. Altern Ther Health Med. 2024.
Kwon DA, Kim YS, Kim SK, Baek SH, Kim HK, et al. Antioxidant and antifatigue effect of a standardized fraction (HemoHIM) from , , and . Pharm Biol. 2021;59:391. doi:10.1080/13880209.2021.1900878
Park HJ, Shim HS, Lee S, Hahm DH, Lee H, et al. Anti-stress effects of human placenta extract: possible involvement of the oxidative stress system in rats. BMC Complement Altern Med. 2018;18:149. doi:10.1186/s12906-018-2193-x